Liver Cirrhosis & Liver Transplant
Liver cirrhosis or chronic liver parenchymal disease (CLD) is a fibrotic condition of the liver leading to end-stage liver failure. The common causative factors are hepatitis virus (HBV, HBC), alcohol consumption and obesity (Non-alcoholic steatohepatis or NASH). Among rare causes of cirrhosis is Wilson disease, autoimmune etc. Sometimes the cause of liver cirrhosis is not known and is called cryptogenic liver cirrhosis.
Liver Transplant
Liver cirrhosis in the early stage is managed with medical management and surgery is rarely required. Patients who fail maximum medical management are considered for liver transplant provided they fulfil the transplant criteria. Signs of progressive liver disease are- Bleeding (hematemesis or malena), Ascitis (accumulation of fluid in the abdomen), Hepatic encephalopathy (disoriented or confused), Acute kidney injury (raised serum creatinine), Breathing difficulty (Hepatopulmonary syndrome). In patients with kidney failure along with liver failure combined liver and kidney transplant is advised.
